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Anti-cancer Drug Teniposide Powder CAS: 29767-20-2 Medicine Grade 99%

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Anti-cancer Drug Teniposide Powder CAS: 29767-20-2 Medicine Grade 99%

Brand Name : TINGYI
Model Number : 29767-20-2
Certification : GMP, SGS , ISO 9001:2008 , KOSHER
Place of Origin : China
MOQ : 1g
Price : Contact Us
Payment Terms : Western Union, MoneyGram, Bank Transfer, Bitcoin
Supply Ability : 4 KG/Month
Delivery Time : Within 7 Working Days
Packaging Details : Stealth And Discreet Packaging
Product Name : Teniposide
CAS : 29767-20-2
MF : C32H32O13S
MW : 656.65
Appearance : White Solid
Usage : Anti-cancer
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Product Name:Teniposide
Product Categories:Carbohydrates & Derivatives;Chiral Reagents;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals;Isotope Labelled Compounds;VUMON;API;Inhibitors;Active Pharmaceutical Ingredients
Teniposide Structure
Chemical Properties
Melting point244-247°C
alphaD20 -107° (9:1 chloroform/methanol)
Boiling point650.86°C (rough estimate)
density1.2568 (rough estimate)
refractive index1.5530 (estimate)
storage temp.-20°C Freezer
solubilityDMSO: soluble10mg/mL, clear
pka10.13(at 25℃)
colorwhite to beige
optical activity[α]/D -100 to -115°, c = 1 in chloroform/methanol (9:1)
Usage And Synthesis
AppearanceWhite Solid
UsesA labelled semi-synthetic derivative of Podophyllotoxin. Antineoplastic.
UsesA semi-synthetic derivative of Podophyllotoxin. Antineoplastic.
UsesTeniposide is a podophyllotoxin derivative that causes dose-dependent single- and double-stranded breaks in DNA by inhibiting topoisomerase II. Its cytostatic effects are related to its ability to stabilize the DNA-topoisomerase II complex during DNA replication, inducing DNA damage and cellular apoptosis. Teniposide has been widely used in the treatment of various cancers including, small cell lung cancer, malignant lymphoma, breast cancer, oral squamous cell carcinoma, and acute lymphoblastic leukemia.
DefinitionChEBI: A furonaphthodioxole that is a synthetic derivative of podophyllotoxin with anti-tumour activity; causes single- and double-stranded breaks in DNA and DNA-protein cross-links and prevents repair by topoisomerase II binding.
General DescriptionTeniposide is available in 50-mg ampules with Cremophor ELfor IV administration in the treatment of acute lymphoblasticleukemia (ALL). The agent is more potent as an inhibitor oftopoisomerase II. The pharmacokinetics of teniposide issimilar to that of etoposide; however, the more lipophilic teniposideis more highly protein bound (99%) and less isexcreted unchanged in the urine (10%–20%). There is alsogreater overall metabolism of teniposide; however, CYP3A4-mediated conversion to the active catechol is slower comparedwith etoposide. Elimination occurs primarily in the urine witha terminal elimination half-life of 5 hours.
Safety ProfilePoison by intraperitoneal and subcutaneous routes. An experimental teratogen. Human systemic effects by ingestion and intravenous route: anorexia, nausea or vomiting, leukopenia, agranulocytosis and aplastic anemia of the blood, bone marrow changes, and hair changes. Experimental reproductive effects. Human mutation data reported. When heated to decomposition it emits very toxic fumes of SOx.

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the product is very good. Whether it is a powder, or liquid, yes, we all
know, our liquid better.

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customs situation, constantly updated, improved our packaging, we guarantee
that you receive it within 3-5 to your product.

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lucky, you buy our powder, we can tell you the method of making the liquid
If you buy a liquid, we will tell you how to filter. We absolutely
guarantee that you can very safely use our products

Packaging & Delivery

1.Sufficient stock, so delivery promptly very day is OK after receive the payment.

2.Well-trained and disciplined packing team:provide unique& safe ways to ship 10g-100kg powers at one time to customers

3.Professional logistic agent We make sure of fast delivery and secure shipping.

4.Packing pictures and tacking code are provided within 24 hours after receiving the payment.Updated tracking information will be provided every other day.

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